Diabetic retinopathy is one of the leading causes of vision loss worldwide, and early automated detection from retinal images is critical to timely treatment. This paper explores a quantum machine learning approach that integrates classical deep feature extraction and dimensionality reduction with a variational quantum circuit inspired by Grover’s algorithm. The model encodes retinal image features into a compact quantum representation and employs iterative quantum amplitude amplification to improve classification accuracy. Experiments conducted on the APTOS 2019 dataset demonstrate that this hybrid quantum-classical method achieves performance comparable to classical Support Vector Machine classifiers, a positive indicator given the early stage of quantum machine learning. These findings highlight the promise of quantum-enhanced techniques for advancing medical image analysis.

Quantum Machine Learning-Based Detection of Retinopathy in Retinal Images of Diabetic Patients

Pero, Chiara;
2026-01-01

Abstract

Diabetic retinopathy is one of the leading causes of vision loss worldwide, and early automated detection from retinal images is critical to timely treatment. This paper explores a quantum machine learning approach that integrates classical deep feature extraction and dimensionality reduction with a variational quantum circuit inspired by Grover’s algorithm. The model encodes retinal image features into a compact quantum representation and employs iterative quantum amplitude amplification to improve classification accuracy. Experiments conducted on the APTOS 2019 dataset demonstrate that this hybrid quantum-classical method achieves performance comparable to classical Support Vector Machine classifiers, a positive indicator given the early stage of quantum machine learning. These findings highlight the promise of quantum-enhanced techniques for advancing medical image analysis.
2026
Inglese
Inglese
Lecture Notes in Computer Science
Workshops and competitions hosted by the 23rd International Conference on Image Analysis and Processing, ICIAP 2025
16170
91
101
11
9783032113801
9783032113818
Springer Science and Business Media Deutschland GmbH
2025
ita
Diabetic Retinopathy Detection
PCA Feature Reduction
Quantum Machine Learning
Variational Quantum Circuit
No
4
none
Cascone, Catello; Nappi, Michele; Pero, Chiara; Polsinelli, Matteo
273
info:eu-repo/semantics/conferenceObject
4 Contributo in Atti di Convegno (Proceeding)::4.1 Contributo in Atti di convegno
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14085/53042
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