Adjuvant therapy with tablets containing sodium jaluronate, carbomer and xantam gum for gerd pharyngitis

Introduction: Chronic pharyngitis is one of the most frequent diseases of the upperaerodigestive pathways. Gastro-esophageal reflux plays an important role in the gthis disease. In fact, the excessive exposure of the pharynx to the gastric contents leads to achronic irritation of the upper airways.On the basis of the foregoing, the study of the present work aims to document the effect ofpastilles composed of xanthan gum, sodium hyaluronate, mannitol, sodium hydrogencarbonate, sorbitol, citric acid, aspartame, vitamin C, aroma, zinc citrate dihydrate.variation of salivary pH, of the symptomatology and of the objective picture in subjectsaffected by secondary interest in acidity of the oral cavity.Materials and methods: 50 subjects were recruited. They were enrolled by the affiliatedusers to three ENT centers and supported by a gastroenterologist (Naples), 50 (25 malesand 25 females) with average age of 37aa, Min 6 aa, Max 65 aa patients affected bysecondary to acidity of the oral cavity. For each patient an objective examination wasperformed and then the salivary pH changes were evaluated, using indicator maps, andfurthermore, the Reflux Symptoms Index (RSI) and Reflux Finding Scores (RFS) wereadministered before, during and after therapy to monitor the subjectivity of thesymptomatology and the laryngeal objective picture.Results: The survey performed allowed to establish a clear improvement in all phases ofthe study, both as regards the effects on pH, both on the side of the symptomatology and onthe laryngeal objective.Discussion: The motivation for improving the clinical condition of the subjects is due to thetherapeutic properties of the substances used. In particular: the hyaluronic acid has aregenerating power of the mucosa; carbomer and Xanthana Gum have a viscoelasticbehavior and contribute to the potency of ac. High molecular weight hyaluronic acidthrough the formation of a hydrocomplex of high tolerability mucoadhesive polymers.Conclusions: Undoubtedly it is a product capable of restoring the physiological conditionsof the oral cavity and the very first airways and their use not only acts as a restoration of thephysiological conditions of the oral cavity, but also as a preventive action for theappearance of local and systemic diseases.