Thyroid hormone excess may cause bone loss predisposing to fragility fractures. An increased risk of fractures has been reported even in patients exposed to a mild excess of thyroid hormones, as it occurs during either over-replacement of hypothyroidism or thyrotropin-suppressive therapy for differentiated thyroid carcinoma. This article deals with pathophysiological and clinical aspects concerning skeletal fragility caused by exposure to thyroid hormone excess, with a specific focus on biochemical, densitometric and fracture data of patients with primary subclinical thyrotoxicosis.

Subclinical thyrotoxicosis and bone

Frara S.;
2018-01-01

Abstract

Thyroid hormone excess may cause bone loss predisposing to fragility fractures. An increased risk of fractures has been reported even in patients exposed to a mild excess of thyroid hormones, as it occurs during either over-replacement of hypothyroidism or thyrotropin-suppressive therapy for differentiated thyroid carcinoma. This article deals with pathophysiological and clinical aspects concerning skeletal fragility caused by exposure to thyroid hormone excess, with a specific focus on biochemical, densitometric and fracture data of patients with primary subclinical thyrotoxicosis.
2018
Bone mineral density
L-thyroxine
Osteoporosis
Thyroid hormones
Thyrotoxicosis
Thyrotropin
Vertebral fractures
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14085/48299
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