We study the osteoinductive effect of the hyaluronic acid (HA) by using an esterifiedlow-molecular HA preparation (EHA) as a coadjuvant in the grafting processes to producebone-like tissue in the presence of employing autologous bone obtained from intra-oral sites,to treat infra-bone defects without covering membrane.We report on 9 patients with periodontal defects treated by EHA and autologous grafting (4males and 5 females, all non smokers, with a mean age of 43,8 years for females, 40,0 yearsfor males and 42 years for all the group, in good health) with a mean depth of 8.3 mm of theinfra-bone defects, as revealed by intra-operative probes. Data were obtained at baselinebefore treatment and after 10 days, and subsequently at 6,9, and 24 months after treatment.Clinical results showed a mean gain hi clinical attachment (gCAL) of 2.6mm of the treated sites, confirmedby radiographic evaluation. Such results suggest that autologous bone combined with EHAseems to have good capabilities in accelerating new bone formation in the infra-bone defects.
Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects
BALLINI, ANDREA;
2009-01-01
Abstract
We study the osteoinductive effect of the hyaluronic acid (HA) by using an esterifiedlow-molecular HA preparation (EHA) as a coadjuvant in the grafting processes to producebone-like tissue in the presence of employing autologous bone obtained from intra-oral sites,to treat infra-bone defects without covering membrane.We report on 9 patients with periodontal defects treated by EHA and autologous grafting (4males and 5 females, all non smokers, with a mean age of 43,8 years for females, 40,0 yearsfor males and 42 years for all the group, in good health) with a mean depth of 8.3 mm of theinfra-bone defects, as revealed by intra-operative probes. Data were obtained at baselinebefore treatment and after 10 days, and subsequently at 6,9, and 24 months after treatment.Clinical results showed a mean gain hi clinical attachment (gCAL) of 2.6mm of the treated sites, confirmedby radiographic evaluation. Such results suggest that autologous bone combined with EHAseems to have good capabilities in accelerating new bone formation in the infra-bone defects.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
