It is news of 28 October 2022 that the Pharmacovigilance Risk Assessment Committee of the European Medicines Agency has recommended to add heavy menstrual bleeding among the side effects of unknown frequency inside the package insert of nucleoside-modified messenger ribonucleic acid vaccines to prevent coronavirus disease 2019 (COVID-19). The decision has been made in the light of the numerous reports of unexpected menstrual changes or abnormal uterine bleeding following COVID-19 vaccination. Here we advance a possible involvement of the particular adenohypophyseal microcirculation in these strange and still unexplained events.

Apropos of menstrual changes and abnormal uterine bleeding after COVID-19 vaccination

Roncati, Luca
;
2023-01-01

Abstract

It is news of 28 October 2022 that the Pharmacovigilance Risk Assessment Committee of the European Medicines Agency has recommended to add heavy menstrual bleeding among the side effects of unknown frequency inside the package insert of nucleoside-modified messenger ribonucleic acid vaccines to prevent coronavirus disease 2019 (COVID-19). The decision has been made in the light of the numerous reports of unexpected menstrual changes or abnormal uterine bleeding following COVID-19 vaccination. Here we advance a possible involvement of the particular adenohypophyseal microcirculation in these strange and still unexplained events.
2023
Abnormal uterine bleeding
Adenohypophysis microcirculation
CD31, cluster of differentiation 31
COVID-19 vaccination
COVID-19, coronavirus disease 2019
Coronavirus disease 2019 (COVID-19)
EMA, European Medicines Agency
Fenestrated capillaries
Heavy menstrual bleeding
Menstrual changes
PA, pituitary apoplexy
PRAC, Pharmacovigilance Risk Assessment Committee
SARS-CoV-2, severe acute respiratory syndrome coronavirus 2
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2)
modRNA, nucleoside-modified messenger ribonucleic acid
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14085/19691
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