APRILE, DOMENICO

APRILE, DOMENICO  

Dipartimento di Scienze della Vita, della Salute e delle Professioni Sanitarie  

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A comparative study on normal and obese mice indicates that the secretome of mesenchymal stromal cells is influenced by tissue environment and physiopathological conditions 1-gen-2020 Ayaz-Guner, S.; Alessio, N.; Acar, M. B.; Aprile, D.; Ozcan, S.; Di Bernardo, G.; Peluso, G.; Galderisi, U.
An Example of Neuro-Glial Commitment and Differentiation of Muse Stem Cells Obtained from Patients with IQSEC2-Related Neural Disorder: A Possible New Cell-Based Disease Model 1-gen-2023 Al Sammarraie, Sura Hilal Ahmed; Aprile, Domenico; Meloni, Ilaria; Alessio, Nicola; Mari, Francesca; Manata, Marianna; Lo Rizzo, Caterina; Di Bernardo, Giovanni; Peluso, Gianfranco; Renieri, Alessandra; Galderisi, Umberto
Different stages of quiescence, senescence, and cell stress identified by molecular algorithm based on the expression of ki67, rps6, and beta-galactosidase activity 1-gen-2021 Alessio, N.; Aprile, D.; Cappabianca, S.; Peluso, G.; Di Bernardo, G.; Galderisi, U.
Germicidal lamps using UV-C radiation may pose health safety issues: a biomolecular analysis of their effects on apoptosis and senescence 1-gen-2024 Alessio, Nicola; Ambrosino, Alessia; Boggi, Andrea; Aprile, Domenico; Pinto, Iole; Galano, Giovanni; Galderisi, Umberto; Di Bernardo, Giovanni
IGFBP5 is released by senescent cells and is internalized by healthy cells, promoting their senescence through interaction with retinoic receptors 1-gen-2024 Alessio, Nicola; Aprile, Domenico; Peluso, Gianfranco; Mazzone, Valeria; Patrone, Deanira; Di Bernardo, Giovanni; Galderisi, Umberto
IGFBP7 is a key component of the senescence-associated secretory phenotype (SASP) that induces senescence in healthy cells by modulating the insulin, IGF, and activin A pathways 1-gen-2024 Siraj, Yesuf; Aprile, Domenico; Alessio, Nicola; Peluso, Gianfranco; Di Bernardo, Giovanni; Galderisi, Umberto
Impact of environmental microplastic exposure on HepG2 cells: unraveling proliferation, mitochondrial dynamics and autophagy activation 1-gen-2025 Najahi, H.; Alessio, N.; Venditti, M.; Lettiero, I.; Aprile, D.; Oliveri Conti, G.; Cappello, T.; Di Bernardo, G.; Galderisi, U.; Minucci, S.; Ferrante, M.; Banni, M.
Lineage specification into GABAergic, glutamatergic, dopaminergic, and astrocytic phenotypes using MUSE stem cells: a novel approach for modeling neurodegenerative and psychiatric disorders 1-gen-2025 Aprile, Domenico; Patrone, Deanira; Al Sammarraie, Sura Hilal Ahmed; Alessio, Nicola; Peluso, Gianfranco; Di Bernardo, Giovanni; Galderisi, Umberto
Loss of hierarchical imprinting regulation at the Prader-Willi/Angelman syndrome locus in human iPSCs 1-gen-2018 Pólvora-Brandão, Duarte; Joaquim, Mariana; Godinho, Inês; Aprile, Domenico; Álvaro, Ana Rita; Onofre, Isabel; Raposo, Ana Cláudia; Pereira De Almeida, Luís; Duarte, Sofia T; Da Rocha, Simão T
Low-Level Radiofrequency Exposure Does Not Induce Changes in MSC Biology: An in vitro Study for the Prevention of NIR-Related Damage 1-gen-2019 Alessio, N; Santoro, E; Squillaro, T; Aprile, D; Briccola, M; Giubbini, P; Marchesani, R; Muoio, Mr; Lamberti, M.
Mesenchymal Stromal Cell (MSC) Isolation and Induction of Acute and Replicative Senescence. 1-gen-2024 Samiminemati, A; Shahzaib, M; Moriello, C; Alessio, N; Aprile, D; Squillaro, T; Di Bernardo, G; Galderisi, U.
Meta-analysis of senescent cell secretomes to identify common and specific features of the different senescent phenotypes: a tool for developing new senotherapeutics 1-gen-2023 Oguma, Yo; Alessio, Nicola; Aprile, Domenico; Dezawa, Mari; Peluso, Gianfranco; Di Bernardo, Giovanni; Galderisi, Umberto
Methods to Detect and Compare Cellular and Mitochondrial Changes in Senescent and Healthy Mesenchymal Stem Cells 1-gen-2024 Samiminemati, A; Shahzaib, M; Moriello, C; Alessio, N; Aprile, D; Squillaro, T; Di Bernardo, G; Galderisi, U
Methods to Investigate the Secretome of Senescent Cells 1-gen-2024 Samiminemati, Afshin; Aprile, Domenico; Siniscalco, Dario; Di Bernardo, Giovanni
Multipotent/pluripotent stem cell populations in stromal tissues and peripheral blood: exploring diversity, potential, and therapeutic applications 1-gen-2024 Aprile, Domenico; Patrone, Deanira; Peluso, Gianfranco; Galderisi, Umberto
MUSE Stem Cells Can Be Isolated from Stromal Compartment of Mouse Bone Marrow, Adipose Tissue, and Ear Connective Tissue: A Comparative Study of Their In Vitro Properties 1-gen-2021 Aprile, D; Alessio, N; Demirsoy, Ih; Squillaro, T; Peluso, G; Di Bernardo, G; Galderisi, U.
Progression of irradiated mesenchymal stromal cells from early to late senescence: Changes in SASP composition and anti-tumour properties 1-gen-2023 Alessio, Nicola; Burak Acar, Mustafa; Squillaro, Tiziana; Aprile, Domenico; Ayaz-Güner, Şerife; Di Bernardo, Giovanni; Peluso, Gianfranco; Özcan, Servet; Galderisi, Umberto
Role of glycosphingolipid SSEA-3 and FGF2 in the stemness and lineage commitment of multilineage differentiating stress enduring (MUSE) cells 1-gen-2023 Aprile, Domenico; Alessio, Nicola; Squillaro, Tiziana; Di Bernardo, Giovanni; Peluso, Gianfranco; Galderisi, Umberto
Terpenes: natural compounds found in plants as potential senotherapeutics targeting senescent mesenchymal stromal cells and promoting apoptosis 1-gen-2025 Mazzone, Valeria; Alessio, Nicola; Aprile, Domenico; Galano, Giovanni; De Rosa, Roberto; Schiraldi, Chiara; Di Bernardo, Giovanni; Galderisi, Umberto
The interactome era: Integrating RNA-seq, proteomics, and network biology to decode cellular senescence 1-gen-2026 Shahzaib, M; Aprile, D; Squillaro, T; Alessio, N; Peluso, G; Di Bernardo, G; Galderisi, U.